On the Nature of the Toxic Component of the Somatic Antigen of Shigella Paradysenteriae Type Z (flexner)
نویسندگان
چکیده
From the chemical evidence presented it appears that the toxicity associated with the somatic antigen of Type Z Sh. paradysenteriae may be attributed to an entity distinct from the known components of the complex. That this substance is neither the protein, the lipid, nor the carbohydrate component of the antigen is evident. Because of its lability to chemical manipulation, the nature of the toxic component, has not yet been ascertained.
منابع مشابه
STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI IlL ANTIBODY RESPONSE IN MAN FOLLOWING THE ADMINISTRATION OF THE SPECIFIC ANTIGEN OF TYPE V SHIGELLA PARADYSENTERIAE (FLEXNER)* BY ELY
The prophylactic immunization of man against bacillary dysentery has proved to be a difficult problem. The severe reactions evoked by the toxic microorganisms used in vaccines (1, 2), the multiplicity of bacterial types encountered in the disease, and the difficulties experienced in evaluating the efficacy of vaccines are all factors which have impeded progress in the control of the disease by ...
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Boivin and his collaborators have investigated in some detail the decomposition of the specific antigens of Gram-negative microorganisms by hydrogen and hydroxyl ions (1). Under conditions of relatively mild acid treatment it was found that antigens derived from a variety of unrelated microorganisms were dissociated into their constituent components, a phospholipid and a serologically active po...
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The present study aims to define the taxonomic position of that group of dysentery bacteria commonly known as Shigella paradysenteriae, var. sonnei (Bergey, 1934). Most of the material on which this work is based has been recently isolated in this laboratory but a number of type strains of the species from The National Collection of Type Cultures in London, England, have been included for compa...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 92 شماره
صفحات -
تاریخ انتشار 1950